Year(s)  /  Region, Area, City or State  /  Disease
 
 

1657 / Boston / Measles

1687 / Boston / Measles

1690 / New York / Yellow Fever

1713 / Boston / Measles

1729 / Boston / Measles

1732-1733 / Worldwide / Influenza

1738 / South Carolina / Smallpox

1739-1740 / Boston / Measles

1747 / Connecticut, New York, Pennsylvania, South Carolina / Smallpox

1759 / North America / Measles

1761 / North America and West Indies / Influenza

1772 / North America / Measles

1775 / North America (especially in North East) / Unknown

1775-1776 / Worldwide / Influenza

1783 / Dover, Delaware (was extremely fatal) / Bilious Disorder

1788 / Philadelphia and New York / Measles

1793 / Vermont / (a "putrid" fever) and Influenza

1793 / Virginia (killed 500 in 5 counties in 4 weeks) / Influenza

1793 / Philadelphia / Yellow Fever

1793 / Harrisburg, PA (many unexplained deaths) / Unknown

1793 / Middletown, Pennsylvania (many mysterious deaths) / Unknown

1794 / Philadelphia, Pennsylvania / Yellow Fever

1796-1797 / Philadelphia, Pennsylvania / Yellow Fever

1798 / Philadelphia, Pennsylvania (one of the worst) / Yellow Fever

1803 / New York / Yellow Fever

1820-1823 / Nationwide (started at Schuylkill River & spread) / "Fever"

1831-1832 / Nationwide (brought in by English Immigrants) / Asiatic
Cholera

1832 / New York and other major cities / Cholera

1833 / Columbus, Ohio / Cholera

1833-34 / Kentucky / Cholera

1834 / New York City, New York / Cholera

1837 / Philadelphia / Typhus

1841 / Nationwide (especially severe in the South) / Yellow Fever

1847 / New Orleans / Yellow Fever

1847-1848 / Worldwide / Influenza

1848-1849 / North America / Cholera

1849 / New York / Cholera

1850 / Nationwide / Yellow Fever

1850-1851 / North America / Influenza

1851 / Coles County, Illinois, The Great Plains, and Missouri / Cholera

1852 / Nationwide (New Orleans 8,000 died that summer) / Yellow Fever

1855 / Nationwide / Yellow Fever

1857-1859 / Worldwide (one of the largest epidemics) / Influenza

1860-1861 / Pennsylvania / Smallpox

1865-1873 / Philadelphia, New York, Boston, New Orleans, Baltimore,
Memphis, Washington DC / A series of recurring epidemics of Smallpox,
Cholera, Typhus, Typhoid, Scarlet Fever, Yellow Fever, and Influenza

1873-1875 / North America & Europe / Influenza

1878 / New Orleans (last great epidemic) / Yellow Fever

1885 / Plymouth, Pennsylvania / Typhoid

1886 / Jacksonville, Florida / Yellow Fever

1918 / Worldwide (high point year) more people were hospitalized in WWI
from this epidemic than wounds. US Army training camps became death
camps, with 80% death rate in some camps. / Influenza or Spanish Flu

  Finally, these specific instances of cholera were mentioned:

     Date   Location            Epidemic
     1833   Columbus, Ohio  Cholera
     1834   New York City    Cholera
     1849   New York            Cholera
     1851   Coles County, Illinois   The Great Plains Missouri   Cholera
 

Sent in by Donata Boyle